Bechets syndrome (mouth, eyes, ulcers)

Mouth | Allergy & Immunology | Bechets syndrome (mouth, eyes, ulcers) (Disease)


Description

Behçets disease, also known by other names like, Morbus Behçet, or Silk Road disease, is a rare systemic vasculitis that is characterized by the presence of mucous membrane ulceration and ocular involvements.

Behçets syndrome is an immune inflammatory disorder producing recurrent mouth and genital ulcers. Behçets syndrome is an autoimmune disorder in which the body produces antibodies that attack its own tissues.

The most common symptoms are: sores in the mouth, sores on the sex organs, other skin sores, swelling of parts of the eye, pain, swelling and stiffness of the joints. More serious problems can include meningitis, blood clots, inflammation of the digestive system and blindness. Additionally, patients may present with erythema nodosum, cutaneous pustular vasculitis, and lesions similar to pyoderma gangrenosum. There is no specific pathological testing or technique available for the diagnosis of the disease.

Causes and Risk factors

The cause of this abnormal immune reaction is unknown, but it may be triggered by viral infection.

Diagnosis and Treatment

Diagnosis of Behçets disease is based on clinical findings including oral and genital ulcers, skin lesions such as erythema nodosum, acne, or folliculitis, ocular inflammatory findings and a pathergy reaction.

Given its rarity, the optimal treatment for acute optic neuropathy in Behçets disease has not been established. Early identification and treatment is essential. Current treatment is aimed at easing the symptoms, reducing inflammation, and controlling the immune system. High dose Corticosteroid therapy is indicated for severe disease manifestations. ...