Vulvar Squamous Cell Carcinoma or Tumor

Pelvis | Oncology | Vulvar Squamous Cell Carcinoma or Tumor (Disease)


Description

Vulvar cancer include 4% of all gynecological cancers and typically affects women in old age. Vulvar carcinoma vulvar intraepithelial neoplasia is different from a non-invasive epithelial lesions that can progress to carcinoma in situ squamous cell cancer and Pagets disease in the vulva. Most lesions originated in the labia, especially in the greater labia. Other sites are the clitoris and fork. While injuries are more common with age once young women with risk factors may also be affected.

Verrucous carcinoma of the vulva is a subtype of squamous cell cancer and tends to occur as a slow-growing condilom. Approximately 5% of vulvar cancers are caused by melanoma vulva. These melanomas behave like melanoma in other locations and can affect a much younger population. Squamous cell carcinoma from melanoma has a high tendency to metastasize.

Typically a lesion is present as a nodule or ulcer, often associated with itching, irritation, bleeding and local elimination of substance. Also dysuria, dyspareunia and pain may be noted. Embarrassment because symptoms may not be presented by the patient. Melanomas tend to produce darker skin coloring. Adenocarcinoma can arise from Bartholin glands and cause a painful lump. Examination of the vulva is a part of gynecologic evaluation and may show ulceration, a lump or mass.

Causes and Risk factors

Cancer etiology is unclear, however, some conditions such as squamous dysplasia condiloma or may precede the development of cancer. Human papillomavirus is suspected to be a possible etiologic factor in vulvar cancer. Patients infected with HIV tend to be more prone to vulvar cancers.

Smokers also tend to be exposed to high risk. Most vulvar cancers are squamous cell carcinomas arising from the origins of vulvar tissue epidermis. Carcinoma in situ is a precursor to squamous cell cancer basal membrane before invading.

Diagnosis and Treatment

The elderly treatment may be complicated by interference with other pathological conditions. Squamous lesions tend to be unifocal, with local extension and expansion of local lymphatic system. The tumor may invade adjacent organs such as vagina, urethra and rectum. ...