Discoid lupus erythematosus (led)


Skin | - Others | Discoid lupus erythematosus (led) (Disease)


Description

Discoid lupus erythematosus (DLE) is a chronic skin condition of sores with inflammation and scarring favoring the face, ears, and scalp and at times on other body areas. These lesions develop as a red, inflamed patch with a scaling and crusty appearance. The center areas may appear lighter in color with a rim darker than the normal skin.

It is unclear whether discoid lupus erythematosus is a separate disease or a milder version of systemic lupus erythematosus (SLE), which can affect any of the body’s organs or tissues. Around five per cent of people with DLE go on to develop SLE and around 20 per cent of people with systemic lupus erythematosus develop DLE.

The symptoms of discoid lupus erythematosus may be constant or sporadic. Not everyone who has discoid lupus erythematosus will have the same type of rash or rashes in the same locations. The word “discoid” refers to the disk shape of the lesions that make up the skin rash. The rash may be red, scaly and raised and usually does not itch. It may develop in areas that get sun exposure, such as the scalp and neck. It is also possible to develop rashes in the vagina or mouth. Discoid lupus erythematosus may also affect the hair, causing it to lose its color.

Causes and Risk factors

The cause of discoid lupus erythematosus is not known. However, it is believed to be an autoimmune disorder in which the immune system abnormally targets the skin, resulting in inflammation and rash. Risk factors for developing a discoid lupus erythematosus outbreak include exposure to sunlight and cigarette smoke.

Diagnosis and Treatment

Physical exam is performed to evaluate the skin lesions. A skin biopsy may be performed to confirm the diagnosis.

Treatment for discoid lupus erythematosus includes corticosteroids to reduce the inflammation caused by the immune response. ...