Loefflers syndrome (pulmonary eosinophilia)

Chest | Pulmonology | Loefflers syndrome (pulmonary eosinophilia) (Disease)


Loeffler syndrome or pulmonary eosinophilia is characterized by the presence of para-hilar or sub-clavicular pulmonary infiltrates, labile, usually linked to high mechanical and allergic phenomena to the presence of parasite larvae in the alveoli.

Causes and Risk factors

Inhaled or ingested extrinsic factors, including medications and infectious agents (e. g. parasites, fungi, mycobacteria), may trigger an eosinophilic immune response. This may be mild and self-limited, as in Loeffler syndrome.

Most cases of simple pulmonary eosinophilia are caused by parasitic infections or drugs; however, no cause is identified in one third of patients.

Diagnosis and Treatment

If Loefflers syndrome occurs because of an allergic reaction a drug, your doctor will most likely tell you to discontinue the use of the drug. If the condition is caused by an infection from fungus or parasites, antibiotics and anti-parasitic medication are the common treatment. Loefflers syndrome will usually go away without needing treatment, but it is always important to see a doctor to avoid possible complications. Complications are possible, but are not likely to occur with Loefflers syndrome. ...

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