AstraZeneca | Accolate (Medication)


Accolate is indicated for the prophylaxis and chronic treatment of asthma in adults and children 5 years of age and older. It works over a long period of time to prevent asthma attacks but will not help to relieve an asthma attack when it is occurring. Asthma sufferers should always have their fast-acting asthma relief medication on hand to deal with attacks.

Zafirlukast, the generic name for Accolate, belongs to a group of medications known as leukotriene receptor antagonists. It works by blocking chemicals produced by the body called leukotrienes. Leukotrienes cause the lining of the breathing passages of the lung to swell. When used regularly, zafirlukast helps to reduce inflammation in the lining of the airways to make breathing easier. ...

Side Effect:

Contact your doctor if you experience these side effects and they are severe or bothersome:abdominal pain; diarrhea; headache; infection; muscle aches; nausea; rash; vomiting.

Check with your doctor as soon as possible if any of the following side effects occur:flu-like illness, rash, pins and needles or numbness of arms or legs, and severe sinusitis.

Stop taking the medication and seek immediate medical attention if any of the following occur:dark urine; discoloured or pale stools; fatigue or weakness; flu-like symptoms; loss of appetite; itching; nausea; pain on the right side of your stomach (just below ribs); yellow skin or eyes; vomiting. ...


Before taking zafirlukast, tell your doctor or pharmacist if you are allergic to leukotriene blockers (e. g. , montelukast); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems.

Before using this medication, tell your doctor or pharmacist your medical history, especially if you have ever had liver problems. Accolate is contraindicated in patients with hepatic impairment or cirrhosis; it has not been studied in patients with hepatitis or in long term studies of patients with cirrhosis.

Caution is advised when using this drug in the elderly because they may be more sensitive to the side effects of the drug, especially headache, diarrhea and nausea.

Accolate is contraindicated in children under 12 years of age until safety information is available.

During pregnancy and breastfeeding is not recommended to use this medicine without your doctor's advice. ...