Grifols Bilogicals | Alphanate (Medication)


Alphanate is a high purity solvent detergent and heat treated preparation of human coagulation factor VIII (antihemophilic factor), freeze-dried, Ph. Eur. Alphanate also contains human von Willebrand factor at pharmacologically effective levels.

This medication works by temporarily raising levels of factor VIII or von Willebrand factor in the blood to aid in clotting. This drug is used to treat or prevent bleeding episodes in adults with hemophilia A. It is also used to treat injury-related bleeding episodes in adults and children with von Willebrand disease. ...

Side Effect:

Call your doctor at once if you have a serious side effect such as:easy bruising, increased bleeding episodes; bleeding from a wound or where the medicine was injected; low fever with skin rash, and joint pain, swelling, or stiffness; sudden numbness or weakness, especially on one side of the body; sudden severe headache, confusion, problems with vision, speech, or balance; black, bloody, or tarry stools; coughing up blood or vomit that looks like coffee grounds; or nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Less serious side effects may include:constipation; swelling, stinging, or irritation where the injection was given; skin rash or itching; swelling in your hands or feet; pain in your arms or legs; chills; or dizziness.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. ...


It doesn't have to be used for those with severe VWD undergoing major surgery. Contains human plasma; monitor for possible infection transmission. Blood groups A, B or AB; large and/or frequent dosing may result in hemolytic anemia. Monitor for development of Factor VIII inhibitors.

There are no known drug interactions for Alphanate (antihemophilic factor/von willebrand factor).

During pregnancy and breastfeeding is not recommended to use this medicine without your doctor advice. ...