Schering-Plough | Anisindione oral (Medication)
Anisindione is indicated for the prophylaxis and treatment of venous thrombosis and its extension, the treatment of atrial fibrillation with embolization, the prophylaxis and treatment of pulmonary embolism, and as an adjunct in the treatment of coronary occlusion. Like phenindione, to which it is related chemically, anisindione exercises its therapeutic action by reducing the prothrombin activity of the blood. ...
In general, they may be divided into 2 categories:those which involve abnormal bleeding and other effects which do not. Hemorrhage and/or necrosis are among the hazards of treatment with any anticoagulant and are the main serious complications of therapy. Adverse reactions reported following therapy with either coumarin or indanedione anticoagulants include:nausea, diarrhea, pyrexia, dermatitis or exfoliative dermatitis, urticaria, alopecia, and sore mouth or mouth ulcers. ...
Tell your doctor your medical history, especially of:bleeding problems (ulcers or lengthy or heavy menstrual periods), diabetes, thyroid disease, liver disease, kidney disease, high blood pressure, heart disease, infections, recent surgery, allergies (especially drug allergies). If you have an illness that causes vomiting, diarrhea or fever for more than a few days, contact your doctor as the effects of this drug may be changed.
Avoid sudden or drastic changes in your diet or alcohol consumption. Especially avoid eating large amounts of foods or vitamin supplements rich in vitamin K (leafy green vegetables, green beans, broccoli, liver, some cheeses).
It is not recommended to use this drug during pregnancy or breastfeeding without your doctor's advice.
It is important that all doctors, dentists and health care professionals caring for you know you are taking this so they can avoid prescribing other medications that may interfere with its effect. ...