Merck & Co. | Aprepitant (Medication)
Aprepitant blocks the actions of chemicals in the body that trigger nausea and vomiting. Aprepitant is used with other medications to help prevent nausea and vomiting caused by cancer drug treatment (chemotherapy). This medication is also used to prevent nausea and vomiting after surgery.
Aprepitant works by blocking one of the body's natural substances that causes vomiting. This medication will not treat nausea or vomiting if you already have it. Contact your doctor for further instructions if you are experiencing nausea or vomiting.
Side effects of using this drug may include:tiredness and hiccups may occur. If either of these effects persist or worsen, tell your doctor or pharmacist promptly. Many people using this medication do not have serious side effects.
A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any of the following symptoms of a serious allergic reaction:rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. ...
Do not take aprepitant if you are taking any of the following drugs:cisapride (Propulsid) or pimozide (Orap). These drugs may cause life-threatening interactions when taken together with aprepitant. If you have liver disease, you may need an aprepitant dose adjustment or special tests.
Aprepitant can make birth control pills less effective, resulting in pregnancy. This effect can last for up to 28 days after your last dose of this medication. Ask your doctor about using a non-hormone method of birth control (such as a condom, diaphragm, spermicide) to prevent pregnancy while taking aprepitant and for at least 1 month after your treatment ends.
There are many other drugs that can interact with aprepitant. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you. ...