Sanofi-Aventis | Arava (Medication)


Arava/leflunomide is used to reduce signs/symptoms of active rheumatoid arthritis, inhibit structural damage, and improve physical function. It may be used with aspirin, NSAIDs, and/or low-dose corticosteroids.

This medication is used to treat rheumatoid arthritis, a condition in which the body's defense system (immune system) fails to recognize the body as itself and attacks the healthy tissues around the joints. Arava helps to reduce the joint damage/pain/swelling and helps you to move better. It works by weakening your immune system and decreasing swelling (inflammation). ...

Side Effect:

Diarrhea, nausea, and dizziness may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Unlikely but serious side effects occur, such as:cough, numbness/tingling of hands/feet, hair loss, chest pain, fast/pounding heartbeat, increased thirst/urination, muscle cramp/pain, mental/mood changes, vision changes.

Tell your doctor immediately if any of these rare but very serious side effects occur:easy bruising/bleeding, unusual growths/lumps, swollen glands (lymph nodes), unexplained weight loss, unusual tiredness.

This medication can lower the body's ability to fight an infection. Tell your doctor immediately if you develop any signs of an infection such as fever, chills, or persistent sore throat.

Seek immediate medical attention if you notice any of the following symptoms of a serious allergic reaction:rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. ...


Before taking Arava, tell your healthcare provider if you have any type of allergies. Tell your doctor or pharmacist your medical history, especially of:immune system disorder (e. g. , HIV infection), current/recent infection (e. g. , tuberculosis), cancer, bone marrow/blood disorder, kidney disease, liver disease (e. g. , hepatitis B or C), alcohol abuse, heart disease (e. g. , congestive heart failure), lung disease.

This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Avoid alcoholic beverages since they can make you dizzy and also cause liver disease.

Do not have immunizations/vaccinations without the consent of your doctor, and avoid contact with people who have recently received oral polio vaccine or flu vaccine inhaled through the nose.

Since this medication can increase your risk of developing serious infections, wash your hands well to prevent the spread of infections. Avoid contact with people who have illnesses that may spread to others (e. g. , flu, chickenpox).

This medication must not be used during pregnancy. It may harm an unborn baby. Before starting this medication, women of childbearing age must have a negative pregnancy test before starting this medication.

During pregnancy and breastfeeding is not recommended to use this medicine without your doctor's advice. ...