Eisai | Aciphex (Medication)


Aciphex (rabeprazole) belongs to a group of drugs called proton pump inhibitors. Aciphex decreases the amount of acid produced in the stomach.

Aciphex is used to treat symptoms of gastroesophageal reflux disease (GERD) and other conditions involving excessive stomach acid such as Zollinger-Ellison syndrome. It is also used to promote healing of erosive esophagitis (damage to your esophagus caused by stomach acid). Aciphex may also be given with an antibiotic to prevent gastric ulcer caused by infection with helicobacter pylori (H. pylori). Aciphex is not for immediate relief of heartburn symptoms. ...

Side Effect:

Aciphex like other PPIs has few side effects. The most common side effects are diarrhea, nausea, vomiting, constipation, rash, and headaches. Dizziness, nervousness, abnormal heartbeat, muscle pain, weakness, leg cramps, and water retention rarely occur.

High doses and long-term use (1 year or longer) may increase the risk of osteoporosis-related fractures of the hip, wrist, or spine. Therefore, it is important to use the lowest doses and shortest duration of treatment necessary for the condition being treated. Low magnesium levels, leading to seizures, abnormal heart beats, and tetany (overactive reflexes) has been reported during long-term treatment.


Heartburn is often confused with the first symptoms of a heart attack. Seek emergency medical attention if you have chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, and a general ill feeling. ...


You should not use this medication if you are allergic to Aciphex or to similar medicines such as lansoprazole, esomeprazole, omeprazole, or pantoprazole. Aciphex is not for immediate relief of heartburn symptoms.

Some conditions are treated with a combination of Aciphex and antibiotics. Use all medications as directed by your doctor. ...