Salix | Azasan (Medication)
Azasan/azathioprine is indicated as an adjunct for the prevention of rejection in renal homotransplantations and to reduce signs and symptoms of severe active rheumatoid arthritis. Immunosuppressants such as azathioprine are effective in helping to control the inflammatory process and thus reducing the need for chronic steroid treatment and its related adverse events. ...
The most commonly reported side effects associated with Azasan are leukopenia and/or thrombocytopenia, secondary infections, neoplasia, nausea, vomiting, diarrhea, fever, myalgias, skin rashes, and hepatotoxicity. ...
Chronic immunosuppression with this purine antimetabolite increases risk of neoplasia in humans. Physicians using this drug should be very familiar with this risk as well as with the mutagenic potential to both men and women and with possible hematologic toxicities.
Azasan should be given cautiously when used concomitantly with allopurinol, ACE inhibitors, and other agents affecting myelopoiesis.
Azasan is contraindicated in pregnant and lactating women and in patients who have shown hypersensitivity to this product. ...