Azathioprine


Salix | Azathioprine (Medication)


Desc:

Azathioprine is a prodrug (a precursor of a drug) which is converted in the body to its active form called mercaptopurine (Purinethol). Azathioprine is an immunosuppressant, that is, a drug that is used to suppress the immune system. It is used to treat patients who have undergone kidney transplantation and for diseases in which activity of the immune system is important. ...

Side Effect:

Azathioprine can cause liver toxicity (for example, in less than 1% of rheumatoid arthritis patients). All patients taking azathioprine require regular testing of blood for blood cell counts and liver tests to monitor for side effects of azathioprine. The most common serious side effects of azathioprine involve the cells of the blood and gastrointestinal system.

Other side effects encountered less frequently include fatigue, hair loss, joint pains, and diarrhea.

Tell your doctor immediately if you develop any of the following:unusual skin changes, change in the appearance/size of moles, unusual growths/lumps, swollen glands, swollen or painful abdomen, unexplained weight loss, night sweats, unexplained itching, signs of infection (e. g. , fever, persistent sore throat), easy bruising/bleeding, or unusual tiredness. ...

Precaution:

Before taking azathioprine, tell your health provider if you have any type of allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems.

Before using this medication, tell your doctor or pharmacist your medical history, especially of:kidney disease, liver disease, blood disorders, decreased bone marrow function, history of cancer (such as lymphoma), active infections, certain enzyme disorder (TPMT deficiency).

Do not have immunizations/vaccinations without the consent of your doctor, and avoid contact with people who have recently received polio vaccine by mouth or flu vaccine inhaled through the nose. Since this medication can increase your risk of developing serious infections, wash your hands well to prevent the spread of infections. Avoid contact with people who have illnesses that may spread to others (e. g. , flu, chickenpox).

Use caution with sharp objects like safety razors or nail cutters, and avoid activities such as contact sports to lower the chance of getting cut, bruised, or injured.

Kidney function declines as you grow older. This medication is removed by the kidneys. Therefore, the elderly may be more sensitive to the effects of this drug.

It is recommended that men and women use two effective forms of birth control (e. g. , condoms, birth control pill) while taking this medication. It is not recommended to use this drug during pregnancy or breastfeeding without your doctor's advice. ...