Pfizer | Benefix (Medication)


BeneFIX/Coagulation Factor IX (Recombinant) is a powder and solvent that are mixed together to form a solution for injection. BeneFIX contains the active substance nonacog alfa. BeneFIX is indicated for the control and prevention of bleeding episodes in adult and pediatric patients with hemophilia B (congenital factor IX deficiency or Christmas disease). ...

Side Effect:

Most common side effects include:dizziness, headache, altered taste, light-headedness, nausea, injection site reactions (such as burning or stinging), injection site discomfort, cellulitis (inflammation of the tissues beneath the skin), phlebitis (inflammation of a vein) and the development of antibodies (inhibitors) to factor IX. If antibodies develop, BeneFIX will not work effectively, which may result in a loss of bleeding control.

Hypersensitivity (allergic reactions) has occasionally been seen in patients treated with products containing factor IX. ...


BeneFIX should not be used in people who may be hypersensitive to recombinant coagulation factor IX, to any of the other ingredients, or to hamster proteins.

Before using this medication, tell your healthcare provider your medical history, especially of:other clotting disorders (e. g. , disseminated intravascular coagulation-DIC), recent surgery/procedure, liver disease.

Before having surgery, tell your doctor or dentist that you are using this medication.

During pregnancy and breastfeeding is not recommended to use this medicine without your doctor's advice. ...