Bristol-Myers Squibb | Capozide (Medication)
Capozide/captopril and hydrochlorothiazide tablets is indicated for the treatment of hypertension. The blood pressure lowering effects of captopril and thiazides are approximately additive.
This fixed combination drug may be used as initial therapy or substituted for previously titrated doses of the individual components.
When captopril and hydrochlorothiazide are given together it may not be necessary to administer captopril in divided doses to attain blood pressure control before the next dose. Also, with such a combination, a daily dose of 15 mg of hydrochlorothiazide may be adequate.
Capozide may be used for patients with normal renal function, in whom the risk is relatively low. In patients with impaired renal function, particularly those with collagen vascular disease, Capozide should be reserved for hypertensives who have either developed unacceptable side effects on other drugs, or have failed to respond satisfactorily to other drug combinations. ...
This drug may rarely cause serious (possibly fatal) liver problems. Seek immediate medical attention if you notice any of the following rare but very serious side effects:yellowing eyes/skin, dark urine, severe stomach/abdominal pain, persistent tiredness, persistent nausea/vomiting.
Dizziness, lightheadedness, drowsiness, headache, tiredness, blurred vision, loss of taste, or dry cough may occur as your body adjusts to the medication. You may also experience decreased sexual ability or increased sensitivity to the sun. ...
Before using this medicine, consult your doctor or pharmacist if you have:a history of an allergic reaction that included swelling of the face/lips/tongue/throat (angioedema), an inability to make urine.
In using Capozide consideration should be given to the risk of neutropenia/agranulocytosis. ACE inhibitors (for which adequate data are available) cause a higher rate of angioedema in patients.
This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.
During pregnancy and breastfeeding is not recommended to use this medicine without your doctor's advice. ...