Unknown / Multiple | Adefovir (Medication)


Adefovir is used to treat chronic (long-term) hepatitis B infection (swelling of the liver caused by a virus) in patients who have symptoms of the disease. Adefovir is in a class of medications called nucleotide analogs. It works by decreasing the amount of hepatitis B virus (HBV) in the body.

Adefovir will not cure hepatitis B and may not prevent complications of chronic hepatitis B such as cirrhosis of the liver or liver cancer. Adefovir may not prevent the spread of hepatitis B to other people. ...

Side Effect:

Check with your doctor if any of these most common side effects persist or become bothersome when using Adefovir:diarrhea; gas; headache; indigestion; mild stomach pain; nausea; upset stomach; vomiting; weakness.

Seek medical attention right away if any of these severe side effects occur when using Adefovir:severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bone pain; change in the amount of urine you produce; dizziness or light-headedness; fast breathing; fast or irregular heartbeat; feeling of being unusually cold (especially in the arms or legs); severe or persistent nausea or vomiting; severe or unusual drowsiness; severe stomach or back pain (with or without nausea or vomiting); shortness of breath; sluggishness; symptoms of new or worsening liver problems (eg, dark urine, loss of appetite, pale stools, severe stomach pain, yellowing of the skin or eyes); unusual muscle pain or cramps; unusual tiredness or weakness. ...


Sudden discontinuation of adefovir may worsen the underlying hepatitis B infection. Discontinuation is supervised by a doctor. Adefovir could cause the emergence of strains of HIV that are resistant to treatment. For this reason, HIV tests are performed before starting treatment with adefovir. Adefovir can damage the kidney. The risk of kidney damage is increased in people with existing kidney impairment or those taking drugs that also harm the kidney. Cyclosporine (Neoral), tacrolimus (Rapamune), some antibiotics, and non-steroidal anti-inflammatory drugs are some medication that can cause kidney impairment. Use of NtRTIs has been associated with development of lactic acidosis (elevated levels of lactic acid) and liver enlargement. The risk is greater in women and during prolonged treatment.

Before using this medicine inform your doctor if you have any type of allergies. Tell your doctor if you are using other medicine and if you have or ever have had any of the following conditions:kidney disease, colitis, or stomach problems.

During pregnancy and breastfeeding is not recommended to use this medicine without your doctor's advice. ...