Shire | Agrylin (Medication)


Agrylin, known generically by Anagrelide, is used to treat a certain blood disorder called thrombocythemia, which is caused by your bone marrow making too many platelets. This drug reduces the number of platelets in the bloodstream by blocking their production. Anagrelide is intended for chronic usage and has not been evaluated for treatment of the acute life-threatening complications of thrombocytosis.

Take this medication by mouth with or without food, usually 2 or 4 times a day, at the same time each day, or as directed by your doctor. The dosage is based on your medical condition and response to therapy. You should not increase the dose without your doctor advice. Use this medication regularly in order to get the most benefit from it. ...

Side Effect:

The most common side effects include:dizziness, mild headache; mild rash or itching; constipation, diarrhea, gas; loss of appetite, mild nausea or stomach pain; numbness or tingly feeling in your hands or feet; sore throat, runny or stuffy nose, nosebleed; muscle or joint pain; sleep problems (insomnia); or blurred vision, ringing in your ears. If any of these persists or get worsen, seek medical help.

More serious side effects that can occur and need immediately care are:dry cough, wheezing, night sweats; feeling short of breath, even with mild exertion; swelling, rapid weight gain; fast, pounding, or uneven heartbeats; chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling; sudden numbness or weakness, especially on one side of the body; sudden headache, confusion, problems with vision, speech, or balance; fever, chills, flu symptoms; severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart rate; seizure (convulsions); feeling like you might pass out; black, bloody, or tarry stools, coughing up blood or vomit that looks like coffee grounds; easy bruising or bleeding, unusual weakness; or blood in your urine, painful or difficult urination. ...


Tell your doctor if you are allergic to Agrylin, any of it's ingredients or if you have any other allergies.

Before using this medication, tell your doctor if you have or ever have had any of the following conditions:heart problems like heart attack, heart failure, irregular heartbeat, lung problems, kidney problems, or liver problems.

It is not recommended to drive or use heavy machinery before you are sure you can perform this activity safely.

During pregnancy and breastfeeding do not take Agrylin without your doctor advice. ...