General or Other | - Others | Bleeding Tendency (Symptom)
In the medicine field called hematology, bleeding tendency or predisposition or haemorrhagic diatheses is an unusual susceptibility to bleeding (hemorrhage) mostly due to hypocoagulability, in turn caused by a coagulopathy (a defect in the system of coagulation). Several types are distinguished, ranging from mild to lethal.
Also known as bleeding diathesis, it can be caused by thinning of the skin or impaired wound healing. There are many causes to vessel defects e. g. hereditary like Ehlers Danlos syndrome, nutrient deficiency such as Vitamin C deficiency, steroid induced, aging (senile purpura), certain infections such as streptococcal, meningococcal infections, malignancies - lymphoma, leukemia, etc.
Among the complications of coagulopathies, some of them are caused by their treatments and include: soft tissue bleeding (e. g. deep-muscle bleeding, leading to swelling, numbness or pain of a limb); joint damage, potentially with severe pain and even destruction of the joint and development of arthritis; retinal bleeding; transfusion transmitted infection from blood transfusions that are given as treatment; anemia; exsanguinations (bleeding to death and cerebral hemorrhage).
Hemophilia is not one disease but rather one of a group of inherited bleeding disorders that cause abnormal or exaggerated bleeding and poor blood clotting. The term is most commonly used to refer to two specific conditions known as hemophilia A and hemophilia B. Hemophilia A and B are distinguished by the specific gene that is altered to become defective, fact called mutation, and codes for a defective clotting factor such as protein in each disease. Rarely, hemophilia C is encountered, but its effect on clotting is far less pronounced than A or B.