General or Other | Allergy & Immunology | Weakness (Symptom)


Proximal weakness of two or four limbs suggests muscle dysfunction or, less frequently, the neuromuscular junction or horn cells previously. Proximal weakness that develops in weeks, months or years is usually due to hereditary diseases, inflammatory, metabolic or endocrine. Myopathy occurs frequently symmetrical muscle weakness or scapular pelvic belt. Neuromuscular junction diseases (such as myasthenia gravis) may be manifested by symmetrical proximal weakness, commonly associated with ptosis, diplopia or bulbar weakness and fluctuating as seritate during the day. Proximal weakness of the previous horn cell disease is frequently asymmetric, but the family can be symmetric if. Numbness does not appear in any of these diseases.


Fatigue is the general weakness of the body due to an effort, physically and intellectually. Fatigue or muscle or brain, is manifested by disorders of attention, the perception of psychomotor activity by decreasing efficiency effort, the mistakes in execution the developed activities. In terms of subjective fatigue is more or less vague: a general weakness, which can be defined and localized, with a tone ranging from feeling the need to rest painful states. Fatigue has a defensive side of the body and is accompanied by difficulty concentrating, reducing the physic, pointing out the need at rest. Fatigue is not a disease, it has only temporary consequences on the body.